2014 Fiscal Year Final Research Report
Analysis of B. subtilis biofilm formation
Project/Area Number |
24580113
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Applied microbiology
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Research Institution | Nara Institute of Science and Technology |
Principal Investigator |
KOBAYASHI Kazuo 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 (70324978)
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Project Period (FY) |
2012-04-01 – 2015-03-31
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Keywords | Bacillus subtilis / biofilm |
Outline of Final Research Achievements |
In this study, we show that BslA was an amphiphilic protein that formed a repellent, protective layer on the surface of biofilms. We also show that B. subtilis responds to methyl salicylate, which is a plant signal that induces defense response in plants in response to infection of plant pathogens. In the presence of methyl salicylate, B. subtilis produced poly-gamma-glutamic acid and antibiotics. Poly-gamma-glutamic acid formed capsules, which protected cells against antimicrobials. These findings reveal the resistance mechanism of B. subtilis biofilms and plant-B. subtilis interaction.
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Free Research Field |
微生物学
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