2015 Fiscal Year Final Research Report
Biosynthesis of structurally unique microbial secondary metabolites
| Project/Area Number |
24580166
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Bioproduction chemistry/Bioorganic chemistry
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| Research Institution | Toyama Prefectural University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | 微生物 / 二次代謝 / 生合成 / ポリケチド |
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| Outline of Final Research Achievements |
Elucidation of biosynthetic mechanisms of structurally unique natural products makes it possible to understand the general principle of generation of structure diversity in natural products and utilize biosynthetic enzymes to create new natural products. Furthermore, it can provide useful information for the construction of potential compound library for drug discovery. In this study, we analyzed the biosynthetic origins and biosynthetic genes of several new secondary metabolites discovered in our laboratory from microorganisms and elucidated novel biosynthetic reactions involved in their synthesis.
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| Free Research Field |
天然物化学
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