2014 Fiscal Year Final Research Report
Study of the role of the functional phosphatide in the skin barrier function
| Project/Area Number |
24580169
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Iwate University (2013-2014)
Teikyo Heisei University (2012) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Takuya 広島大学, 生物圏科学研究科, 准教授 (30526695)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 機能性リン脂質 / 皮膚バリア機能 |
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| Outline of Final Research Achievements |
This study investigated the effects of plasmalogens on the skin barrier function in NHEK cells of normal human epidermal keratinocytes and NC/Nga mice of atopic dermatitis model.
PlsEtn enhances the skin barrier function through the assembly and the expression of the TJ proteins in NHEKs.Intake of the food material that increases plasmalogen in body has the improvement effect against the atopic dermatitis in NC/Nga mice.
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| Free Research Field |
脂質生理学
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