Elucidation of mechanism for the development of durability of Gmelina arborea wood based on metabolism of lignans by Trametes versicolor

2014 Fiscal Year Final Research Report

• Project/Area Number: 24580252
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Wood science
• Research Institution: Forestry and Forest Products Research Institute
• Principal Investigator: KAWAMURA Fumio 独立行政法人森林総合研究所, バイオマス化学研究領域, 主任研究員 (80353655)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: グメリナ材 / 木材腐朽菌 / カワラタケ / 抗菌活性発現機構 / リグナン類 / グメリノール / パウロウニン

Outline of Final Research Achievements

Gmelinol and paulownin were estimated as major antifungal constituents (lignans) of Gmelina arborea. These constituents were metabolized by a white-rot fungus, Trametes versicolor, and six metabolites (7'-methoxygmelinol, 7-methoxygmelinol, 7,7'-dimethoxygmelinol, 7'-hydroxygmelinol, 7'-methoxypaulownin and 7,7'-dimethoxypaulownin) were isolated. The antifungal activities of afforded metabolites were assayed using T. versicolor, and the activities were less than that of substrates except for 7'-methoxygmelinol. In contrast, 7'-methoxygmelinol showed higher antifungal activity than substrate (gmelinol), and the yield of this metabolite was very high. Furthermore, gmelinol was rich in the heartwood of G. arborea. The mechanism for the development of durability of G. arborea wood based on metabolic transformation of lignans including gmelinol was presumed.

Free Research Field

天然物化学