2014 Fiscal Year Final Research Report
Development of egg-hatching assays for evaluatingTCBZ resistance of parthenogenic Fasciola sp.
| Project/Area Number |
24580420
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Basic veterinary science/Basic zootechnical science
|
|---|
| Research Institution | Iwate University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | parthenogenic Fasciola / hybridyzation / Fasciola hepatica / diploid |
|---|
| Outline of Final Research Achievements |
Experimental production of TCBZ-resistant parthenogenic Fasciola sp. was attempted due to hybridyzation between Fasciola hepatica and diploid parthenogenic Fasciola sp.(Fg lineage). Hybrid F1 and F2 descendants produced had aberrant meiotic division in their spermatogenesis as well as wild-type parthenogenic Fasciola sp. However, the descendants were proved to be TCBZ-susceptible due to TCBZ administration experiments, and the development of egg-hatching assay turn out not to be ture.
|
| Free Research Field |
寄生虫学
|
