2014 Fiscal Year Final Research Report
Characterization of feline microRNAs:a potential biomarker for diagnosis of feline diabetes and obesity
Project/Area Number |
24580468
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Clinical veterinary science
|
Research Institution | Nippon Veterinary and Life Science University |
Principal Investigator |
SASAKI NORIYASU 日本獣医生命科学大学, 獣医学部, 准教授 (20307979)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Keywords | マイクロRNA / ネコ / 肥満 / 糖尿病 / エクソソーム / バイオマーカー |
Outline of Final Research Achievements |
To characterize novel microRNAs (miRNA) related to obesity and diabetes in cats, we identified the feline miRNA expressed in white adipose tissue (WAT) and exosome with next-generation sequencing. In WAT, we identified 169 of novel feline miRNAs that could regulate expression of their target genes including angiogenesis, adipocyte differentiation and inhibition.
|
Free Research Field |
獣医生化学
|