2014 Fiscal Year Final Research Report
Development of catalytic reactions based on the properties of nonmetallic elements
| Project/Area Number |
24590018
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Chemical pharmacy
|
|---|
| Research Institution | Kitasato University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | FLPs / 有機ホウ素化合物 / 触媒的水素化反応 |
|---|
| Outline of Final Research Achievements |
The synthesis of the designed organoboron compounds and their reactivity for molecular hydrogen were examined. Although triaryl boron compounds bearing bis(pentafluorophenyl) boryl group were highly unstable against air (molecular oxygen) and water, we demonstrated that the introduction of a coordinating group such as pyridine, amide, formyl, or ether to ortho position of aryl bis(pentafluorophenyl)boron increased chemical stabilities and enabled to handle under air. The synthesized organoboron compounds showed no reactivity for molecular hydrogen under various conditions. However, the ether type organoboron compounds with methoxymethyl ether at ortho position indicated the reversibility of the coordination of an ether oxygen atom toward boron(III) center. These observations serve as a guiding principle of catalyst design for hydrogenation reaction.
|
| Free Research Field |
医歯薬学
|
