2017 Fiscal Year Final Research Report
Receptor of vibrioferrin, siderophore of Vibrio parahaemolyticus
| Project/Area Number |
24590529
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Bacteriology (including Mycology)
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2018-03-31
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| Keywords | 腸炎ビブリオ / 鉄 / siderophore |
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| Outline of Final Research Achievements |
Vibrio parahaemolyticus requires iron for its survival and growth. V. parahaemolyticus produces siderophore, vibrioferrin (VF), under iron restriction conditions.
Deletion mutants which lacks VF receptors were prepared, and showed that VF was necessary for growth of V. parahaemolyticus. Monoclonal antibodies against two VF receptors were prepared and showed binding ability with VF receptors. These clones may be useful for V. parahaemolyticus detection. Characterization of these antibodies are undergoing.
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| Free Research Field |
細菌学
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