Evaluation of new radical measurement method using imuno-spin trapping with anti-spin trap antibody

2014 Fiscal Year Final Research Report

• Project/Area Number: 24590718
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Laboratory medicine
• Research Institution: Kyushu University of Health and Welfare
• Principal Investigator: SATO Keizo 九州保健福祉大学, 薬学部, 教授 (00315293)
• Co-Investigator(Kenkyū-buntansha): SHINYA Tomohiro 九州保健福祉大学, 薬学部薬学科, 助教 (60551299)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 酸化ストレス / フリーラジカル / ラジカル捕捉剤 / 抗ラジカル捕捉剤抗体

Outline of Final Research Achievements

Oxidative Stress have important roles in various diseases such as diabetes, infectious disease, inflammatory disease, lung injury and aging. Threrfore, development of a correct and handy method of oxidative stress is desired. So we have developed the new radical measurement method which is stable and high sensitive by using an antibody of a radical trap agent. As a results, It could be confirmed that it can be gauged, a immunostain method, ELISA method and HPLC method. Consequently, I could think this method could contribute to a study of all fields as new oxidation stress measurement.

Free Research Field

酸化ストレスの本体であるフリーラジカルの新規測定法の開発