Molecular epidemiology for depression in cancer

2015 Fiscal Year Final Research Report

• Project/Area Number: 24590831
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: National Cancer Center Japan
• Principal Investigator: Ogawa Asao 国立研究開発法人国立がん研究センター, 先端医療開発センター, 分野長 (10466196)
• Co-Investigator(Kenkyū-buntansha): UCHITOMI Yosuke 国立がん研究センター, 支持療法開発センター, センター長 (60243565)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 疫学 / 分子疫学 / 臨床精神分子遺伝学 / 緩和医療

Outline of Final Research Achievements

Various risk factors for depression in cancer patients have been suggested but have been examined separately in studies with relatively small sample sizes. The present study examined the biopsychosocial risk factors of depression in cancer, focusing on molecular epidemiological factors. We recruited newly diagnosed as having cancer before first line treatment consecutively. We aim to identify comprehensive geriatric assessment (CGA) based clinical factors associated with depression. Logistic regression models were fitted to estimate the odds ratio (OR) to assess the association of various variables with mild to severe depression. And, we exploratory conduct GWAS of depressive symptoms.

Free Research Field

精神腫瘍学