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2014 Fiscal Year Final Research Report

Role of tissue heme protein on the toxicokinetics of carbon monoxide.

Research Project

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Project/Area Number 24590856
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Legal medicine
Research InstitutionKagawa University

Principal Investigator

KINOSHITA HIROSHI  香川大学, 医学部, 教授 (00284357)

Co-Investigator(Kenkyū-buntansha) AMENO Kiyoshi  香川大学, 医学部, 准教授 (50019626)
TANAKA Naoko  香川大学, 医学部, 助教 (60700052)
Project Period (FY) 2012-04-01 – 2015-03-31
Keywords一酸化炭素 / 中毒 / センサーガスクロマトグラフィー / ヘモグロビン / 飽和度 / 体内動態
Outline of Final Research Achievements

We have applied the sensor gas chromatography for the measurement of carboxyhemoglobin (CO-Hb) saturation in blood. It is highly sensitive for carbon monoxide, and it may be applicable for other forensic samples.
No remarkable difference of CO-Hb saturation was observed between heart blood and peripheral venous blood in carbon monoxide related cases. And there was no effect of sample dilution on the value of CO-Hb in case of concentrated blood.

Free Research Field

法医学

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Published: 2016-06-03  

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