2014 Fiscal Year Final Research Report
Impact of residual platelet function on late stent thrombosis after drug-eluting stent implantation
| Project/Area Number |
24591079
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Kawasaki Medical School |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YOJI Neishi 川崎医科大学, 医学部, 講師 (80319946)
KIYOSHI Yoshida 川崎医科大学, 医学部, 教授 (60322583)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | ステント血栓症 / 光干渉断層法 / 冠動脈 / 血小板凝集 |
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| Outline of Final Research Achievements |
To clarify relationship between clopidogrel resistance and intra-stent thrombus formation following drug-eluting stent implantation, 152 stented lesions from 74 patients were enrolled and studied. At follow-up (mean 10 months) after stenting, intra-stent thrombus detected by optical coherence tomography was more frequently found in patients with clopidogrel resistance. In conclusion, clopidogrel resistance may be related to intra-stent thrombus formation after drug-eluting stent implantation.
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| Free Research Field |
医歯薬学
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