2014 Fiscal Year Final Research Report
The development of personalized treatment for patients with COPD
| Project/Area Number |
24591136
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 身体活動性 / COPD / 加速度計 |
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| Outline of Final Research Achievements |
We developed an evaluation method for the physical activity of patients with COPD by using a triaxial accelerometer, Actimarker, which is available in Japan. The duration of physical activity in patients with COPD was significantly reduced at any intensity of activity, and that at greater than or equal to 3.0METs was reduced by 50% compared to that of age-matched healthy subjects. Transdermal tulobuterol, a beta-2 adrenergic agonist, could improve the physical activity, especially at high intensity. There is a flying disc accuracy game with low intensity of activity that is feasible for patients and sufficiently enjoyable that they were motivated to participate repeatedly. Participation in such a game might be an effective intervention to maintain or improve the physical activity of patients with COPD.
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| Free Research Field |
医歯薬学
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