2014 Fiscal Year Final Research Report
Vitmain D signal in parathyrioid tumorigenesis
| Project/Area Number |
24591353
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Metabolomics
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| Research Institution | Osaka City University |
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Principal Investigator |
INABA Masaaki 大阪市立大学, 医学(系)研究科(研究院), 教授 (00176405)
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| Co-Investigator(Kenkyū-buntansha) |
IMANISHI Yasuo 大阪市立大学, 医学(系)研究科(研究院), 講師 (50326253)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 副甲状腺ビタミンD受容体 |
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| Outline of Final Research Achievements |
To examine the role of vitamin D receptor (VDR) in parathyroid cell proliferation, parathyroid tissue specific knockout of VDR was performed using Cre-lox P system in mice. The penetration of VDR knockout in parathyroid was not enough, so that hyperparathyroidism was not developed in these mice.
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| Free Research Field |
内分泌学、腎臓病学
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