2014 Fiscal Year Final Research Report
Involvement of oxidative/nitrosative stress in the alteration of adipocyte-metabolisms induced by early nutritional disorder, and its control
| Project/Area Number |
24591525
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Showa University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 小児 / 栄養 / 肥満 / 脂質異常症 / 糖代謝異常 / 生活習慣病 / 脂肪細胞 / 酸化ストレス |
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| Outline of Final Research Achievements |
I have studied the oxidative / nitrosative stress and adipocytokine levels in cultured adipocytes and animal models with hyper-cytokinemia. Clinically, the effects of nutritional status in early infancy including neonatal period on future growth and the development of life-style related disease are investigated. Furthermore, new methods of evaluation of visceral fat accumulation, new markers of obesity, criteria of non-HDL-C, etc. have been studied by this grant. The obtained results are described in the text.
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| Free Research Field |
医歯薬学
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