2014 Fiscal Year Final Research Report
Characterization of peptide fragment of neurosecretory protein VGF precursor (373-417) in the mouse brain
| Project/Area Number |
24591528
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Nippon Medical School |
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Principal Investigator |
TAKESHI Asano 日本医科大学, 医学部, 准教授 (70277490)
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| Co-Investigator(Kenkyū-buntansha) |
OZAWA Hitoshi 日本医科大学, 医学研究科, 教授 (60169290)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 急性脳症 / 髄液 / ペプチド / 核内蛋白 / VGF |
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| Outline of Final Research Achievements |
The aim of the investigation was to explore the characterization of peptide fragment of neurosecretory protein VGF precursor (373-417) in the brain. We made the antibodies against the peptide and stained the mouse and rat brain tissue. We found the antibodies recognized nuclear protein in the neural cells in cerebral cortex, alveus hippocamp, nigra by immunohistochemistry and western blot. These results suggested the VGF peptide might act as nuclear protein.
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| Free Research Field |
小児科学
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