Resistance Values in the Limbs, as measured by a Multiple-frequency Bioelectrical-impedance Method, are Useful for Estimating the Severity of Kawasaki Disease.

2014 Fiscal Year Final Research Report

• Project/Area Number: 24591578
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Pediatrics
• Research Institution: Kagoshima University
• Principal Investigator: YUICHI Nomura 鹿児島大学, 医歯(薬)学総合研究科, 准教授 (90237884)
• Co-Investigator(Kenkyū-buntansha): EGUCHI Taisuke 鹿児島大学, 医学部歯学部附属病院, 助教 (20535687) ; NISHI Junichiro 鹿児島大学, 大学院医歯学総合研究科, 教授 (40295241)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 川崎病 / 硬性浮腫 / インピーダンス / 重症度評価

Outline of Final Research Achievements

We evaluated the efficacy of resistance values in Kawasaki disease (KD) patients for estimating the severity of KD. Patients and Methods: In 57 patients with the acute phase of KD (before intravenous immunoglobulin; IVIG), 36 with the sub-acute phase, 54 controls, and 23 febrile control, we measured resistance (impedance; IMP) in each child’s total body and extremities using MLT-550N. Corrected IMP values (coIMP; IMP x limb’s cross-sectional area/ limb’s length) were also examined. Results: Percentages of extra-cellular water in KD patients are higher than controls. IMP values were not different among patients with KD and controls. CoIMP values in the forearm or lower leg of patients in the acute phase of KD were higher than those of controls. The values of coIMP of IVIG non-responders at the acute phase were higher than those of responders. Conclusion: Values of co-IMP might be useful for estimating the severity of KD.

Free Research Field

小児科学