2014 Fiscal Year Final Research Report
Follow-up study on the non-transient cases with At-risk mental state (ARMS)
| Project/Area Number |
24591732
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Toho University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TSUJINO Naohisa 東邦大学, 医学部, 講師 (00459778)
NEMOTO Takahiro 東邦大学, 医学部, 准教授 (20296693)
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| Research Collaborator |
INOUE Naomi
YOROZUYA Yuko
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 精神病発症危険状態 / 精神病発症超ハイリスク / 移行例・非移行例 / 統合失調症 |
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| Outline of Final Research Achievements |
Objectives: To observe trajectories of symptoms and psychosocial functioning in patients at ultra-high risk (UHR) for psychosis as well as to investigate the psychosocial predictors of transition to psychosis.
Method: Twenty-two prospectively identified patients fulfilling UHR criteria were followed in one-year longitudinal study. Symptoms and psychosocial functioning were measured at the baseline and after one year follow-up.Result: Among the 15 patients who underwent follow-up evaluation, 6 subjects had converted to full-blown psychosis at one year, and 9 had not. There was a tendency for non-converters to have lower social-functioning at their baseline than the converters.Conclusion: The study suggests the need for treatment targeting not only the prevention of developing psychosis but also targeting the recovery of social-functioning. Further investigation of UHR patients should be considered with longer follow up duration.
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| Free Research Field |
精神医学
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