Prognosis prediction of gastrointestinal cancers based on intratumoral blood flow using contrast enhanced CT

2014 Fiscal Year Final Research Report

• Project/Area Number: 24591771
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kyushu University (2012, 2014); National Hospital Organization, Kyushu Cancer Center (2013)
• Principal Investigator: KOMORI Masahiro 九州大学, 医学(系)研究科(研究院), 研究員 (90529819)
• Co-Investigator(Kenkyū-buntansha): TSURUMARU Daisuke 九州大学, 大学病院, 助教 (90419565) ; ASAYAMA Yoshiki 九州大学, 大学病院, 助教 (40380414) ; MIYASAKA Mitsutoshi 九州大学, 大学病院, 助教 (10457434) ; NISHIMUTA Yusuke 九州大学, 大学病院, 医員 (10635220) ; HONDA Hiroshi 九州大学, 医学研究院, 教授 (90145433)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 胃癌 / 大腸癌 / マルチスライスCT

Outline of Final Research Achievements

In this study, we examined relationship between intratumoral blood flow and prognostic factors of gastric and colorectal cancer using a multi-slice CT.　We treated pathological proven gastric cancers (n=21) and colorectal cancers (n=33). We used multiphasic contrast-enhanced CT (320 detector) for preoperative workup. We performed qualitative and quantitative analyses and evaluated the relationship between the imaging features and prognostic factors of gastric and colorectal cancers. There was no significant difference between enhancement pattern and recurrence of gastric cancers. Colorectal cancers with poor arterial blood flow (contrast enhancement) had association with possibility of high grade pathological malignancy.

Free Research Field

消化管診断