Invention of evaluation method for therapeutic effect of pulmonary hypertension with phase contrast cine MRI

2014 Fiscal Year Final Research Report

• Project/Area Number: 24591782
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: University of the Ryukyus
• Principal Investigator: MURAYAMA Sadayuki 琉球大学, 医学(系)研究科(研究院), 教授 (60239548)
• Co-Investigator(Kenkyū-buntansha): KAMIYA Hisashi 琉球大学, 大学院医学研究科, 助教 (60363678)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: PC-MRI / 肺動脈血流量 / 再現性 / 慢性血栓塞栓性肺高血圧症 / 肺動脈拡張術

Outline of Final Research Achievements

We examined the utility of Phase-contrast MRI (PC-MRI) for evaluation of therapeutic efficacy to pulmonary hypertension. First, we tried to prove the reproducibility of the measured value derived from PC-MRI between the different MR apparatus. The indexes obtained from time flow curve derived from PC-MRI was thought to possess high reliability. Thus, measured values can be used as general values in pulmonary blood flow evaluation. Next, we reported two cases with chronic thromboembolic pulmonary hypertension undergoing balloon pulmonary angioplasty (BPA) where PC-MRI was useful in assessing its therapeutic efficacy. In these two cases, the pulmonary flow volume was increased after BPA.

Free Research Field

放射線診断学