Development and application of viscographic imaging method using diffusion weighted MRI

2015 Fiscal Year Final Research Report

• Project/Area Number: 24591795
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Meiji University of Integrative Medicine
• Principal Investigator: Watanabe Yasuharu 明治国際医療大学, 医学教育研究センター, 講師 (90454537)
• Co-Investigator(Kenkyū-buntansha): UMEDA Masahiro 明治国際医療大学, 医学教育研究センター, 教授 (60223608) ; TAGUCHI Daisuke 明治国際医療大学, 保健医療学部, 講師 (00390112) ; KIMURA Keisaku 明治国際医療大学, 鍼灸, 助教 (50454533) ; MURASE Tomokazu 明治国際医療大学, 医学教育研究センター, 助教 (00708943)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: MRI / 筋 / 水分子 / 粘性 / 動き

Outline of Final Research Achievements

The material properties of passive skeletal muscle are critical to proper function and are frequently a target for therapeutic and interventional strategies. Diffusion tensor imaging (DTI) provides information regarding the movement as well as the direction and speed of tissue water, and it can also be used to visualize the hysteresis of passive time-dependent responses. The purposes of this study were to analyze in detail the water movement in skeletal muscles during pushing stimulation and visualize tissue deformation of the hysteresis in vivo by using DTI.
Deformation was found underneath the stimulated areas during the decompressing phase and in the wide area during the pushing phase. Differences were also found in direction of water movement. In passive time-dependent responses of the skeletal muscles in vivo, these results showed varying deformation regions between the pushing and decompressing phases.

Free Research Field

MRI医学