2014 Fiscal Year Final Research Report
Significance of gadoxetic acid-enhanced MR imaging signal intensity for predicting the efficacy of hepatic arterial infusion chemotherapy in hepatocellular carcinoma
| Project/Area Number |
24591814
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NISHIE Akihiro 九州大学, 医学(系)研究科(研究院), 講師 (20457427)
ASAYAMA Yoshiki 九州大学, 大学病院, 講師 (40380414)
USHIJIMA Yasuhiro 九州大学, 医学(系)研究科(研究院), 助教 (40432934)
TAKAYAMA Yukihisa 九州大学, 医学(系)研究科(研究院), 助教 (60546563)
HONDA Hiroshi 九州大学, 医学(系)研究科(研究院), 教授 (90145433)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 肝細胞癌 / MRI / Gd-EOB-DTPA / 肝動注化学療法 |
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| Outline of Final Research Achievements |
The purpose of the present study was to clarify the relationship in hepatocellular carcinoma cases between the tumor signal intensity in the hepatobiliary phase of gadoxetic acid-enhanced MR imaging and the patient response to hepatic arterial infusion chemotherapy. The higher intensity group in the hepatobiliary phase of gadoxetic acid-enhanced MR imaging showed a significantly higher progression-free survival rate than the lower intensity group. Patients with HCCs of higher intensity in the hepatobiliary phase of gadoxetic acid-enhanced MR imaging can respond better to hepatic arterial infusion chemotherapy.
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| Free Research Field |
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