2014 Fiscal Year Final Research Report
Development of novel interventional therapy for advanced pancreatic cancer
| Project/Area Number |
24591819
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Nara Medical University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 膵癌 / 血管塞栓術 / 球状塞栓物質 / 薬剤溶出性ビーズ |
|---|
| Outline of Final Research Achievements |
To develop novel interventional therapy for liver metastases from pancreatic cancer. First, in ex vivo study, feasibility of bead-TAE using arterial port system was examined. Beads under 500um in size could pass through the port. Next, for hypovascular liver metastases, bland-TAE using beads was conducted, and high anti-tumor effect was shown. In a study of irinotecan eluting beads, using VX2 tumor rabbits, 40um beads TACE was conducted and histologically beads were distributed inside of the tumors with high necrotic ratio and also pharmacological advantage was shown.
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| Free Research Field |
インターベンショナル・ラジオロジー
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