2015 Fiscal Year Final Research Report
The study of anti-tumor with anti-metastasis under combination of 4-methylumbelliferone on X-irradiation against cancer cell
| Project/Area Number |
24591831
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Hirosaki University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MONZEN Satoru 弘前大学, 大学院保健学研究科, 助教 (20514136)
TERASHIMA Shingo 弘前大学, 大学院保健学研究科, 助教 (00583733)
YOSHINO Hironori 弘前大学, 大学院保健学研究科, 助教 (10583734)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | ４－メチルウンベリフェロン / 放射線治療 / 転移 |
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| Outline of Final Research Achievements |
Radiotherapy is generally effective against cancer, however distant metastasis cannot be controlled by radiotherapy alone. Our experiments are studied to develop new radiotherapy combined with 4-Methylumbelliferone (MU) in order to prevent metastasis of cancer cells. On this study, the treatment of radiation combined with MU showed anti-cancer and anti-metastatic effects compared with radiation alone. MU is hoped to apply in a clinical setting as anti-metastatic drug on radiotherapy.
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| Free Research Field |
放射線腫瘍生物学
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