2014 Fiscal Year Final Research Report
The fragility of macrovesicular fatty liver grafts during ischemia reperfusion injury
| Project/Area Number |
24591868
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KUDO Atsushi 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 (20376734)
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| Co-Investigator(Kenkyū-buntansha) |
田中 真二 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 (30253420)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | microcirculation |
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| Outline of Final Research Achievements |
It has been well known that sinusoidal reperfusion imbalance is observed in the liver grafts. In xenobiotic detoxification capacity of macrovesicular fatty liver grafts, the sinusoidal reperfusion of zonal heterogenity may determine the graft viability in the liver with or without Macrovesicular fatty liver grafts. Sinusoidal perfusion verocity derived from hepatic artery clamping examined anatomically, physiologically, and biochemically in the liver with or without macrovesicular fatty liver.
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| Free Research Field |
肝臓生理学
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