2014 Fiscal Year Final Research Report
Development of a new treatment for small-for-size liver graft injury after living donor liver transplantation by bone morphogenetic protein (BMP)-7.
| Project/Area Number |
24591995
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Chiba University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YOSHITOMI Hideyuki 千葉大学, 医学部附属病院, 講師 (60375631)
KATO Atsushi 千葉大学, 大学院医学研究院, 講師 (70344984)
SHIMIZU Hiroaki 千葉大学, 大学院医学研究院, 准教授 (80272318)
MIYAZAKI Masaru 千葉大学, 大学院医学研究院, 教授 (70166156)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 肝臓病学 / 移植・再生医療 |
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| Outline of Final Research Achievements |
In this study, we revealed that bone morphogenetic protein (BMP)-7 has protective effect for small-for-size (SFS) liver graft injury in rat SFS liver transplantation. Our data and further elucidation of a mechanism of BMP-7 function contribute to a new treatment for small-for-size liver graft injury after living donor liver transplantation without portal inflow modulation.
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| Free Research Field |
医歯薬学
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