2014 Fiscal Year Final Research Report
Detection of pancreatic cancer by serum microRNA
| Project/Area Number |
24592039
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Tokyo Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KURODA Masahiko 東京医科大学, 医学部, 教授 (80251304)
YUICHI Nagakawa 東京医科大学, 医学部, 講師 (20349484)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 膵癌 / microRNA / 早期診断 |
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| Outline of Final Research Achievements |
We analyzed the serum microRNA in patients with pancreatic cancer by microarray. The results showed that hsa-miR-188-5p, hsa-miR-1275 and hsa-miR-3648 were significantly higher in pancreatic cancer patients than those in healthy volunteer or patients with benign pancreatic disorders. Especially, miR-1275 increased 3.6 times in average. In future, we have a plan to analyze the role and function of these microRNA in pancreatic cancer.
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| Free Research Field |
膵臓外科
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