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2014 Fiscal Year Final Research Report

Detection of pancreatic cancer by serum microRNA

Research Project

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Project/Area Number 24592039
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Digestive surgery
Research InstitutionTokyo Medical University

Principal Investigator

TSUCHIDA Akihiko  東京医科大学, 医学部, 教授 (50207396)

Co-Investigator(Kenkyū-buntansha) KURODA Masahiko  東京医科大学, 医学部, 教授 (80251304)
YUICHI Nagakawa  東京医科大学, 医学部, 講師 (20349484)
Project Period (FY) 2012-04-01 – 2015-03-31
Keywords膵癌 / microRNA / 早期診断
Outline of Final Research Achievements

We analyzed the serum microRNA in patients with pancreatic cancer by microarray. The results showed that hsa-miR-188-5p, hsa-miR-1275 and hsa-miR-3648 were significantly higher in pancreatic cancer patients than those in healthy volunteer or patients with benign pancreatic disorders. Especially, miR-1275 increased 3.6 times in average. In future, we have a plan to analyze the role and function of these microRNA in pancreatic cancer.

Free Research Field

膵臓外科

URL: 

Published: 2016-06-03  

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