Numerical simulation of blood flow in perfusion from arteries: observational study and theory

2014 Fiscal Year Final Research Report

• Project/Area Number: 24592044
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Thoracic surgery
• Research Institution: Hirosaki University
• Principal Investigator: FUKUDA Wakako 弘前大学, 医学(系)研究科(研究院), 助教 (90598715)
• Co-Investigator(Kenkyū-buntansha): FUKUDA Ikuo (50344594) ; DAITOKU Kazuyuki (50374822)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 外科 / 流体工学 / コンピューター・シミュレーション / 体外循環 / 大腿動脈送血 / 脳塞栓 / 動脈硬化症

Outline of Final Research Achievements

Extracorporeal circulation is an important adjunctive technique for cardiovascular surgery. In cardiopulmonary bypass, blood with low oxygen content is withdrawn from large veins, introducing artificial lung to exchange oxygen and bicarbonate. Oxygenated blood is introduced directly into the aorta or through peripheral arteries. Arterial perfusion from the femoral artery is one of the easiest procedure because of easiness of exposure and enough diameter. This method is convenient for reoperation or minimally invasive cardiac surgery. However, atheroembolism due to retrograde perfusion from the femoral artery is emerging problem in elderly patients. We studied flow velocity and shear stress in the aorta and its branches using computed simulation technique. We compared two method for femoral artery perfusion: direct cannulation vs. side-armed graft method. Flow velocity and shear stress was lower in the side-army graft method than that in direct cannulation.

Free Research Field

心臓血管外科