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2015 Fiscal Year Final Research Report

Simultaneous bicoherence analysis of occipital and frontal electroencephalograms in awake and anesthetized subject to assess the conscious level

Research Project

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Project/Area Number 24592313
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

Hayashi Kazuko  京都府立医科大学, 医学(系)研究科(研究院), 客員講師 (40285276)

Research Collaborator SAWA Teiji  京都府立医科大学, 医学研究科, 教授 (10206013)
Project Period (FY) 2012-04-01 – 2016-03-31
Keywordsα波 / 加齢 / 睡眠 / 意識 / 麻酔 / コヒーレンス / 後頭 / 覚醒
Outline of Final Research Achievements

A prominent alpha rhythm accompanying high bicoherence growth is often seen in occipital awake EEGs in younger persons. With the induction of anesthesia, the occipital alpha bicoherence peak disappears and a frontal alpha bicoherence peak appears. The occipital neural network is spatially differently modulated from the frontal EEG in the regulation of consciousness and anesthesia.
On the other hand, in the elderly, δ-θ bicoherence increased under deeper anaesthesia, similarly to healthy adults, but alpha bicoherence growth was small irrespective of anaesthesia level. Frontal α bicoherence growth in the elderly EEG did not change with the depth of sevoflurane anaesthesia, contrasting with the healthy adult showing anaesthesia-dependent change in alpha activity, indicating that the neural network creating alpha waves may be modulated by aging.

Free Research Field

麻酔科学、脳神経科学

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Published: 2017-05-10  

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