2014 Fiscal Year Final Research Report
Identification and clinical application of novel biomarkers for neuroendocrine differentiation of prostate cancer
| Project/Area Number |
24592391
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Hiroshima University |
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Principal Investigator |
MATSUBARA Akio 広島大学, 医歯薬保健学研究院, 教授 (10239064)
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| Co-Investigator(Kenkyū-buntansha) |
TEISHIMA Jun 広島大学, 医歯薬保健学研究院, 講師 (20397962)
YASUI Wataru 広島大学, 医歯薬保健学研究院, 教授 (40191118)
INOUE Shogo 広島大学, 病院, 助教 (90457177)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 前立腺癌 / 神経内分泌分化 / 去勢抵抗性 / RegIV |
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| Outline of Final Research Achievements |
Mechanism of molecules identified by CAST method in castration-resistance and neuroendocrine differentiation of prostate cancer cells have been investigated through cell-biological analysis, and the possibility as novel biomarkers of these molecules have been suggested through the experiments for expression in prostate cancer tissues and the measurement of serum concentration.
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| Free Research Field |
泌尿器科学
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