2015 Fiscal Year Final Research Report
Study of the efficacy of the replacement therapy of zinc in pregnant women and the fetal environment
| Project/Area Number |
24592467
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KANAYAMA Naohiro 浜松医科大学, 医学部, 教授 (70204550)
ITO Hiroaki 浜松医科大学, 医学部附属病院, 教授 (70263085)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | 亜鉛 / 鉄 / 胎児 / 貧血 |
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| Outline of Final Research Achievements |
The supplementation of zinc + iron significantly increased the hemoglobin compared to the iron alone for anemia pregnant women in the second trimester. The fetus growth did not show significant difference, but accepted fetal growth in zinc + iron group using a Z score. The umbilical cord blood zinc level was significantly higher than the maternal zinc level. Meconium stained amniotic fluid contained the higher level of zinc and iron. The level of copper was high and zinc was low in the maternal blood. The level of copper was low and zinc was high in the umbilical cord blood. We suggest a possible presence of selective trace elements transfer system in human placenta. Zinc might make the fetal environments better in amniotic fluid, fetal blood, and maternal blood.
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| Free Research Field |
周産期
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