2015 Fiscal Year Final Research Report
Functional analysis of FMR1 pritein as an etiological factor for primary insufficiency.
| Project/Area Number |
24592491
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | St. Marianna University School of Medicine |
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Principal Investigator |
Ishizuka Bunpei 聖マリアンナ医科大学, 医学部, 教授 (80097336)
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| Co-Investigator(Kenkyū-buntansha) |
ITOH MASANORI 東京医科歯科大学, 教養部, 教授 (30257349)
TAKAHASHI NORIYUKI 聖マリアンナ医科大学, 医学部, 研究技術員 (80267450)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | FMR1 / POI / 原発性卵巣不全 / 卵巣 |
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| Outline of Final Research Achievements |
The findings are that 1) FMR1 protein is expressed in oocyte stage-specifically, 2) ovaries from follicular atresia model animals can explain the pathogenesis of POI and 3) a new medical protocol for the treatment of POI patients are developed.
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| Free Research Field |
生殖内分泌
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