2014 Fiscal Year Final Research Report
Secretory mechanism of the submucosal gands in the eustachian tube and its regulation
| Project/Area Number |
24592539
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Nihon University (2014)
Tohoku University (2012-2013) |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 耳管腺 / 耳管機能 / 耳管開放症 |
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| Outline of Final Research Achievements |
The secretory mechanism in the middle ear and tuba mucosa has crucial roles in strategies of the treatment and prevention of otitis media. In the present study, submucosal tubal glands could be identified. Primary culture could reveal the expression of acquaporin in the gland cells, suggesting of the significance of the secretion mechanism of the gland. In 301 ears suffering from patulous eustachian tube, the tubal function test was performed. Three types of the impedance wave forms could be revealed as the positive finding indicative of patulous eustachian tube.
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| Free Research Field |
医学
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