The possibility of positron emission tomography (PET) as a predictive tool for preoperative evaluation of second implant in bilateral cochlear implant patients

2015 Fiscal Year Final Research Report

• Project/Area Number: 24592554
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Otorhinolaryngology
• Research Institution: University of Miyazaki
• Principal Investigator: Tono Tetsuya 宮崎大学, 医学部, 教授 (80145424)
• Co-Investigator(Kenkyū-buntansha): USHISAKO YASUAKI 宮崎大学, 医学部, 助教 (10185001) ; NAGAMACHI SHIGEKI 宮崎大学, 医学部, 准教授 (40180517) ; NAGANO YUKI 宮崎大学, 医学部, 助教 (50404405) ; OKUDA TAKUMI 宮崎大学, 医学部, 助教 (60404456) ; FUKUDOME SHINJI 宮崎大学, 医学部, 助教 (80404458) ; TAKASHI GOTO 宮崎大学, 医学部, 助教 (20600612) ; NAKASHIMA TAKAHIRO 宮崎大学, 医学部, 助教 (90315375)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 後迷路機能評価 / 人工内耳 / 高度感音難聴 / PET-CT / 電気蝸牛刺激検査

Outline of Final Research Achievements

The purpose of this study is to evaluate the efficacy of positron emission tomography (PET) as a tool of preoperative examination which predicts the usefulness of second implant in bilateral cochlear implant (CI) user. Seventeen patients with bilateral profound sensorineural hearing loss were examined. Glucose metabolism of the brain was measured with PET/CT after and before electrical auditory stimulation. Correlation between the postoperative results and primary auditory cortex activation of patients who underwent unilateral CI was not observed. In the pediatric patients who underwent bilateral CI, Good postoperative hearing results of the second implant were exhibited in a case that had the primary auditory cortex activation. On the other hand, in case the primary auditory cortex activation was not recognized exhibited poor postoperative results. Preoperative evaluation using PET/CT is potentially useful as test to predict the effect of the second implant.

Free Research Field

耳科学