2014 Fiscal Year Final Research Report
Methylation analysis by using next generation DNA sequencer in HNSCC.
| Project/Area Number |
24592594
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MISAWA Kiyoshi 浜松医科大学, 医学部附属病院, 講師 (90334979)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | ゲノム網羅的メチル化解析 / 頭頸部癌 / 中咽頭癌 / HPV / 次世代シークエンサー |
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| Outline of Final Research Achievements |
In the present study, we prospectively analyzed HPV realted oropharyngeal cancer and normal side tonsil by using next generation DNA sequencer.
We analyzed the promoter methylation of 3 genes (MAL, SLC5A5, NUP85) in 133 HNSCC and in matching 42 normal tissues.
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| Free Research Field |
耳鼻咽喉科
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