Candidate gene analysis of well-known genes in primary open-angle glaucoma patients utilizing custom-made gene chip

2014 Fiscal Year Final Research Report

• Project/Area Number: 24592636
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: MORI Kazuhiko 京都府立医科大学, 医学(系)研究科(研究院), 講師 (40252001)
• Co-Investigator(Kenkyū-buntansha): MATSUDA Akira 順天堂大学, 医学(系)研究科(研究院), 准教授 (00312348) ; IKEDA Yoko 京都府立医科大学, 医学(系)研究科(研究院), 客員講師 (00433243) ; TASHIRO Kei 京都府立医科大学, 医学(系)研究科(研究院), 教授 (10263097) ; KINOSHITA Shigeru 京都府立医科大学, 医学(系)研究科(研究院), 教授 (30116024) ; UENO Morio 京都府立医科大学, 医学(系)研究科(研究院), 助教 (40426531) ; NAKANO Masakazu 京都府立医科大学, 医学(系)研究科(研究院), 准教授 (70381944)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 眼遺伝学

Outline of Final Research Achievements

In this study, we performed a case-control analysis in 609 single nucleotide polymorphisms (SNPs), which are selected from our original clinical database collected for more than 15 years and from our genomic information of more than 4000 cases, between primary open-angle glaucoma (POAG) patients and normal controls, and found several new SNPs that related to Japanese POAG patients.

Free Research Field

ゲノム医科学