A basic research for the development of corneal surgeries that considered the quality of vision and corneal biomechanics

2014 Fiscal Year Final Research Report

• Project/Area Number: 24592669
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Osaka University
• Principal Investigator: MAEDA Naoyuki 大阪大学, 医学(系)研究科(研究院), 寄附講座教授 (00273623)
• Co-Investigator(Kenkyū-buntansha): TSUJIKAWA Motokazu 大阪大学, 大学院医学系研究科, 寄附講座教授 (70419472) ; KOH Shizuka 大阪大学, 大学院医学系研究科, 助教 (00570590) ; SOMA Takeshi 大阪大学, 大学院医学系研究科, 特任助教(常勤) (70582401)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 視覚の質 / 生体力学 / 角膜形状 / 波面収差 / 手術

Outline of Final Research Achievements

To develop new corneal surgeries with good quality of vision, we created the methodology for evaluating higher-order aberrations due to donor and host cornea following keratoplasty. For the early detection of contraindication of LASIK, the characteristics of corneal topography in keratoconus and its related diseases were determined. In addition, the importance of the treatment of dry eye after corneal surgeries was suggested from the loss of visual function in dry eye patients with normal corneal shape. Also, corneal biomechanical analysis indicated the rigidity of the cornea following current keratoplasties were weaker than that in normal eye.

Free Research Field

眼科