2014 Fiscal Year Final Research Report
Elucidation of recurrence / metastasis related gene using mapping array of oral cancer
| Project/Area Number |
24593009
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Kanagawa Dental College (2014)
Tokyo Dental College (2012-2013) |
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Principal Investigator |
YAMAMOTO Nobuharu 神奈川歯科大学, 歯学研究科(研究院), 准教授 (60385185)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 口腔がん / DNAマッピングアレイ / ヘテロ接合性消失（LOH） |
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| Outline of Final Research Achievements |
Molecular biological search and identification of cancer have a variety of clinical significance. Microarray, proteomics and metabolome analyses are powerful analytical methods for rapid screening of tumor markers. As the results, it was revealed that a number of genes are specifically expressed in oral cancers. As the results of CAN and LOH analyses of the entire genome, three candidate gene loci (D1S1189, D1S2151, D1S2595) were identified on 1q31.1 region.
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| Free Research Field |
口腔外科
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