2014 Fiscal Year Final Research Report
Development of the treatment that targeted an arachidonate cascade of the oral cancer neighborhood environment
| Project/Area Number |
24593022
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OGA Noritaka 北海道大学, 歯学研究科, 助教 (40548202)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 腫瘍血管内皮 |
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| Outline of Final Research Achievements |
We found that COX-2/ prostaglandin E2 (PGE2) and prostacyclin (PGI2) was expressed highly in a tumor endothelial cells.In others to use expensive molecular target medicine for as a treatment strategy of the vascularization inhibition therapy, the COX-2/ prostaglandin E2 (PGE2) inhibitor could used cancer treatment.Targeting tumor angiogenesis is an established strategy for cancer therapy.
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| Free Research Field |
腫瘍
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