Elucidation of mechanical condition for controlling destructive alveolar bone resorption under diabetic hyperglycemia

2014 Fiscal Year Final Research Report

• Project/Area Number: 24593072
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: Hokkaido University
• Principal Investigator: SATO Yoshiaki 北海道大学, 歯学研究科(研究院), 准教授 (00250465)
• Co-Investigator(Kenkyū-buntansha): KUSAKABE Toyohisa 北海道大学, 大学病院, 助教 (80322824)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 糖尿病 / 高血糖 / 矯正的歯の移動 / 骨吸収 / 3次元 / 低出力超音波パルス

Outline of Final Research Achievements

Destructive alveolar bone resorption may be occurring by orthodontic tooth movement under diabetic hyperglycemia. The aims of this study were, to know the 3-dimensional alveolar bone resorption rate by orthodontic treatment under hyperglycemia, to know optical orthodontic force in such cases, and to know if the Low-Intensity Pulsed Ultrasound could recover this absorbed alveolar bone effectively.
The results could conclude that destructive alveolar bone resorption was occurred in hyperglycemia condition compared to normal condition in rats, and the Low-Intensity Pulsed Ultrasound could formate faster bone absorption.

Free Research Field

歯科矯正学