The exploitation of effective tooth movement by the specific osteoclast inhibitor and the system of prevention on periodontal disease.

2014 Fiscal Year Final Research Report

• Project/Area Number: 24593115
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: Aichi Gakuin University
• Principal Investigator: GOTO Shigemi 愛知学院大学, 歯学部, 教授 (60142577)
• Co-Investigator(Kenkyū-buntansha): MIYAZAWA Ken 愛知学院大学, 歯学部, 教授 (60301636)
• Co-Investigator(Renkei-kenkyūsha): TABUCHI Masako 愛知学院大学, 歯学部, 講師 (30418925)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 歯学 / 矯正学 / 歯周病 / 破骨細胞 / 病理学

Outline of Final Research Achievements

The purpose of this study is making a system which is controlled tooth movement freely by the bone metabolism and controlled resorption of alveolar bone in periodontal disease. Firstly, it was established an experimental mouse model of periodontitis-inducing. This research suggested that placement of the ligature wire around the contact point between teeth was successfully induced alveolar bone resorption. Therefore, the present report provides a new animal model of periodontitis.
Further studies are needed to investigate and development the system of tooth movement controlled by the bone metabolism.

Free Research Field

歯科矯正学