Investigation of the relationship between aspiration pneumonia onset and aspiration observed by videoendoscopy

2015 Fiscal Year Final Research Report

• Project/Area Number: 24593146
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Social dentistry
• Research Institution: Osaka University
• Principal Investigator: Nohara Kanji 大阪大学, 歯学研究科(研究院), 准教授 (20346167)
• Co-Investigator(Kenkyū-buntansha): TAKAI ETSUKO 大阪大学, 歯学部附属病院, 医員 (30532642)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 摂食嚥下障害 / 嚥下内視鏡 / 誤嚥 / 誤嚥性肺炎 / 気道線毛輸送機能

Outline of Final Research Achievements

The subjects comprised 68 dysphagic patients. The presence of respiration-derived fever within 6 months following the videoendoscopy (VE) was assessed, and the VE results and presense of fever during course were compared. There no significant difference in the presence of fever between aspirators and non-aspirators observed by VE. These results suggested that there was a mismatch between the presence of aspiration on the test and the presence of fever.
The mucociliary transport function was evaluated within 54 dysphagic patients. Subject group who had developed fever showed a significantly worse than subject group without fever. These results suggest that a deteriorated mucociliary transport function indicate an increased risk of aspiration pneumonia.

Free Research Field

医歯薬学