Relationship between periodontitis and salivary antioxidant activity by ESR

2014 Fiscal Year Final Research Report

• Project/Area Number: 24593155
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Social dentistry
• Research Institution: The University of Tokushima
• Principal Investigator: TAMAKI Naofumi 徳島大学, ヘルスバイオサイエンス研究部, 准教授 (20335615)
• Co-Investigator(Kenkyū-buntansha): ITO Hiro-o 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授 (40213079) ; YOSHINO Fumihiko 神奈川歯科大学, 歯学研究科(研究院), 准教授 (20308307)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 歯周病 / 酸化ストレス / 抗酸化力

Outline of Final Research Achievements

The aim of present study was to measure the direct salivary antioxidant activity toward superoxide and hydroxyl radical. Moreover, we clarified the relationship between serum reactive oxygen metabolite (ROM) level and levels of immunoglobulin G antibody to periodontal pathogens. As a result, serum ROM levels were positively correlated with antibody titers to Porphyromonas gingivalis, Prevotella intermedia and Eikenella corrodens.

Free Research Field

予防歯科学