2014 Fiscal Year Final Research Report
Biological plausibility for causal association of the exposure to second-hand smoke with early childhood caries
| Project/Area Number |
24593182
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Fukuoka Dental College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OJIMA Miki 大阪大学, 歯学研究科, 助教 (20263303)
TANAKA Keiko 愛媛大学, 医学研究科, 助教 (40341432)
HARESAKU Satoru 福岡歯科大学, 口腔歯学部, 講師 (10330961)
YAMAMOTO Mito 福岡歯科大学, 口腔歯学部, 医員 (90435123)
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| Research Collaborator |
WATANABE Takeshi 福岡歯科大学, 口腔歯学部, 准教授 (50191771)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | う蝕 / 乳歯 / 受動喫煙 / 妊婦喫煙 / たばこ対策 / 萌出 / 1歳６カ月児健康診査 / 因果関係 |
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| Outline of Final Research Achievements |
Evidence is accumulated to infer causal association of second-hand smoke (SHS) exposure with early childhood caries (ECC), indicating anticipation of dental involvement in control of smokeless tobacco and creation of smoke-free environment. Among potential biological plausibility, early eruption in 1.5 year-old children, which was defined as eruption of 16 teeth or more, was associated independently with SHS exposure. Early eruption was increased by 26% in children with SHS exposure. While early eruption was increased by 29% among children without exposure in utero, elevation was 42% in children whose mother smoked during pregnancy (78% vs 55%). Though effect of unknown confounder cannot be ruled out, SHS exposure could be accounted for the causal association. Injury of gene, which is potential cause of later obesity of children who exposed to SHS, may account for early eruption. Future study is warranted to clarify whether early eruption is observed in secondary dentition.
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| Free Research Field |
口腔保健学
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