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2014 Fiscal Year Final Research Report

Quantitative measurement of a new small animal SPECT/CT scanner with a semiconductor detector

Research Project

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Project/Area Number 24601008
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field 医学物理学・放射線技術学
Research InstitutionKanazawa University

Principal Investigator

KOBAYASHI Masato  金沢大学, 健康増進科学センター, 助教 (30444235)

Co-Investigator(Kenkyū-buntansha) KAWAI Keiichi  金沢大学, 保健学系, 教授 (30204663)
HANAOKA Hirofumi  千葉大学, 薬学研究科, 助教 (50361390)
Project Period (FY) 2012-04-01 – 2015-03-31
KeywordsSPECT / 半導体検出器 / 分子イメージング / 小動物用イメージング装置 / 定量測定
Outline of Final Research Achievements

In this study, we developed a quantitative measurement on a new small animal SPECT/CT scanners with a semiconductor detecotor.After assessment of performance on the scanners,seinsitivity of pinhole collimators was lower than that of parallel and slit collimators, while resolution was higher. Especially, eXplore speCZT CT120 was superior to another scanner on energy resolution. In addition, attenuation and resolution correction have kept quaitification of radioactive counts.However, we needed to develop new pinhole collimators for mice to yield higher resolution and for rats to yield higher sensitivity. The collimators provided 1.7 times resoulution for mice imaging and 2-3 times sensitivity for rats imaging.

Free Research Field

分子イメージング

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Published: 2016-06-03  

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