Statistical development and application of countermeasures for space deconditioning

2015 Fiscal Year Final Research Report

• Project/Area Number: 24620011
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: 宇宙生命学
• Research Institution: Aichi Medical University
• Principal Investigator: IWASE SATOSHI 愛知医科大学, 医学部, 教授 (90184879)
• Co-Investigator(Kenkyū-buntansha): Nishimura Naoki 愛知医科大学, 医学部, 講師 (40278362) ; Inukai Yoko 愛知医科大学, 医学部, 講師 (10308950) ; Sato Maki 愛知医科大学, 医学部, 助教 (60351102)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 人工重力 / 宇宙飛行デコンディショニング / G耐性 / 筋萎縮 / 骨粗鬆症 / 起立性低血圧 / 長期間臥床 / ヘッドダウンベッドレスト

Outline of Final Research Achievements

We assessed whether space flight deconditioning, induced by microgravity, can be prevented and ameliorated by centrifuge-induced artificial gravity with exercise. Old type centrifuge of 4 m in diameter was remodeled to 2.8 m type centrifuge, enabled to be loaded on board in space station. The first remodeled type made the subjects sit on a rotating chair, however, this was revealed not to load the enough G to the heart. We secondly remodeled the rotating chair lying down on the back with their legs elevated to provide the enough G to the heart. Using the second remodeled type, we performed bedrest study, and found the effectiveness in G-tolerance, bone metabolism, myatrophy, etc. We concluded that the short arm centrifuge of 2.8 m in diameter was effective in prevention and amelioration of space flight deconditioning.

Free Research Field

環境神経生理学