2014 Fiscal Year Final Research Report
Identification of Chronotype and its application of non-pharmacological treatment for mood disorders
| Project/Area Number |
24621003
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
睡眠科学
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| Research Institution | Shiga University of Medical Science |
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Principal Investigator |
YAMADA Naoto 滋賀医科大学, 医学部, 教授 (50166724)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 生体リズム / 時間遺伝子 / 非薬物治療 |
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| Outline of Final Research Achievements |
The purpose of the study is to confirm the method for identifying a chrono-type type using saliva from the subjects, and to examine the validity of the method by comparing the data obtained from questionnaire. The saliva of the subjects was collected every 2 hours from 6 to 20 o'clock.
After creating the cDNA from the RNA extracted from the saliva, each amount of Per3, Nr1d1, Nr1D2 was measured by the real-time PCR. Then, the index of the circadian rhythm (the acrophase, the mesa - the amplitude) was identified using the data.
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| Free Research Field |
精神医学
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