Establishing a new method to analyze neuronal activities of all individual neurons of C. elegans CNS.

2014 Fiscal Year Final Research Report

• Project/Area Number: 24650167
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Neuroscience in general
• Research Institution: Kyushu University
• Principal Investigator: ISHIHARA Takeshi 九州大学, 理学(系)研究科(研究院), 教授 (10249948)
• Co-Investigator(Renkei-kenkyūsha): TERAMOTO Takayuki 九州大学, 大学院理学研究院, 准教授 (90571836) ; KUGE Sayuri 九州大学, 大学院理学研究院, 学術研究員 (50260104)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 神経科学 / イメージング / 線虫 / 情報処理

Outline of Final Research Achievements

To visualize the informational processing in CNS, we planned to device a method that enable us to analyze the activities of all individual neurons in living C. elegans. To do this, we improved a microscopy system, optimized Ca2+ probe and image processing including tracking neurons by pattern matching. By using this system, we succeeded in evaluating more than 20 individual neurons and in observing a synchronous activity.

Free Research Field

行動遺伝学