The study of repetitive transcranial magnetic stimulation in the higher brain dysfunction

2015 Fiscal Year Final Research Report

• Project/Area Number: 24650332
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Jikei University School of Medicine
• Principal Investigator: Hara Takatoshi 東京慈恵会医科大学, 医学部, 助教 (40619889)
• Co-Investigator(Kenkyū-buntansha): WATANABE Syu 東京慈恵会医科大学, リハビリテーション医学講座, 教授 (30256466)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 脳卒中 / 経頭蓋的磁気刺激療法 / 失語症 / エイリアンハンド症候群

Outline of Final Research Achievements

the effects of repetitive transcranial magnetic stimulation in the higher brain dysfunction and Imaging study have not been examined fully. We investigated the change of image in chronic post-stroke patients, pre- and post-intervention, consisting of rTMS and intensive rehabilitation. In Alien hand syndrome, We have the first case of improving AHS and upper limb functions by low-frequency repetitive transcranial magnetic stimulation(rTMS) to the contralesional cerebral hemisphere and intensive occupational therapy. And this technique had the effects reduced inter hemispheric inhibition by fNIRS. In the chronic post-stroke aphasic patients, fMRI-guided LF-rTMS combined with intensive ST affect CBF and contribute to the improvement of language function of post-stroke aphasic patients.

Free Research Field

リハビリテーション科学